Protein Info for RR42_RS19345 in Cupriavidus basilensis FW507-4G11

Annotation: transcription termination/antitermination factor NusG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 193 PF02357: NusG" amino acids 19 to 124 (106 residues), 106 bits, see alignment E=1.2e-34 TIGR00922: transcription termination/antitermination factor NusG" amino acids 21 to 193 (173 residues), 231.4 bits, see alignment E=3e-73 PF00467: KOW" amino acids 142 to 174 (33 residues), 28.5 bits, see alignment 1e-10

Best Hits

Swiss-Prot: 67% identical to NUSG_NEIMA: Transcription termination/antitermination protein NusG (nusG) from Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)

KEGG orthology group: K02601, transcriptional antiterminator NusG (inferred from 97% identity to reh:H16_A3502)

Predicted SEED Role

"Transcription antitermination protein NusG" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YH94 at UniProt or InterPro

Protein Sequence (193 amino acids)

>RR42_RS19345 transcription termination/antitermination factor NusG (Cupriavidus basilensis FW507-4G11)
MTDNAQQEVPAAESPSSKKRWYVVHAYSGMEKSVQRALQERIERAEMQDKFGRILVPSEE
VVEIKGGQKSVTERRFFPGYVLVEMEMTDETWHLVKNTSKVTGFVGGARNRPSPISQKEV
DKIMTQMQEGVEKPRPKTLFEVGEMVRVKDGPFTDFNGNVEEVNYEKSRLRVSVTIFGRA
TPVELEFGQVEKV