Protein Info for RR42_RS18565 in Cupriavidus basilensis FW507-4G11

Annotation: serine/threonine protein phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 377 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 33 to 55 (23 residues), see Phobius details amino acids 66 to 87 (22 residues), see Phobius details amino acids 104 to 126 (23 residues), see Phobius details PF00149: Metallophos" amino acids 152 to 320 (169 residues), 46.8 bits, see alignment E=2.5e-16

Best Hits

KEGG orthology group: K07098, (no description) (inferred from 75% identity to reh:H16_A3359)

Predicted SEED Role

"putative phosphoesterase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y6W8 at UniProt or InterPro

Protein Sequence (377 amino acids)

>RR42_RS18565 serine/threonine protein phosphatase (Cupriavidus basilensis FW507-4G11)
MPPRTTVFVAALVVGLLHGYIGLRLLPDMPVSFAIKALAVAWLALSWPLIPAGLLARRLD
QPWSDALTWVGMLAMGFFSSLLILTLAREVVLLVSAMAGWHPAWLLPGTAAAVPVLALLV
TLVGLFNARRLAQVVEVEVPIAGLPDSLHDFTIVQISDIHVGPTIKRAYLERIVARVNGL
APDAIAITGDLVDGTVRELSRHTAPLGNLKARHGTYFVTGNHEYYVGAEPWITELRGLGL
RVLMNEHVVIGEEEEALVLAGVTDFSAHRFDESHRSDPARALHGAPAVVAARVLLAHQPR
TAPAASTAGFDLQLSGHTHGGQFWPWNLFVPMQQPYTAGLNRHEAMWVYVSRGTGYWGPP
KRFGAPSEITKLRLVRK