Protein Info for RR42_RS17985 in Cupriavidus basilensis FW507-4G11

Annotation: type II secretion system protein F

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 421 transmembrane" amino acids 187 to 211 (25 residues), see Phobius details amino acids 240 to 258 (19 residues), see Phobius details amino acids 394 to 414 (21 residues), see Phobius details PF00482: T2SSF" amino acids 87 to 210 (124 residues), 124.7 bits, see alignment E=1.1e-40 amino acids 291 to 413 (123 residues), 109.3 bits, see alignment E=6.6e-36

Best Hits

Swiss-Prot: 50% identical to TAPC_AERHY: Type IV pilus assembly protein TapC (tapC) from Aeromonas hydrophila

KEGG orthology group: K02653, type IV pilus assembly protein PilC (inferred from 90% identity to reh:H16_A3256)

Predicted SEED Role

"Type IV fimbrial assembly protein PilC" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YK49 at UniProt or InterPro

Protein Sequence (421 amino acids)

>RR42_RS17985 type II secretion system protein F (Cupriavidus basilensis FW507-4G11)
MATRAPAAAARKAAAPTGKPGRKAPTQYLFEWEGKDRKGKAFSGELRAESQAEVNATLRK
QGLTVVKLKKRRAARGKKITQKDIAYFTRQLSTMLKAGIPLLQSIDIIARGHANPNFTQL
LSEIRFDIESGSSMAQAFRRHPRYFDTLYCNLIDAGEQGGILDALLERLSLYMEKTIALK
SQIKSAMIYPIAVLSVAFAVTVILMIFVIPAFKGVFSSFGANLPAPTLVVIAMSDFFVDN
WYLIIGAPIIGITMYIRGLKRSEKVQRASDRLLLKLPIFGSLFRKAVIARWTRTLATMFA
AGTPLVESMESVAGAAGNWVYYDATKEIEQSVRIGTSLTNAMQATHVFDSMVLQMTQIGE
ESGALDNMLLKVAEFYEREVDDAVAAISSLIEPLIIVVLGVLIGGMVVAMYLPIFKLGQV
V