Protein Info for RR42_RS17750 in Cupriavidus basilensis FW507-4G11

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 transmembrane" amino acids 34 to 54 (21 residues), see Phobius details amino acids 62 to 88 (27 residues), see Phobius details amino acids 95 to 114 (20 residues), see Phobius details amino acids 120 to 140 (21 residues), see Phobius details amino acids 162 to 184 (23 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 249 to 269 (21 residues), see Phobius details amino acids 283 to 305 (23 residues), see Phobius details amino acids 312 to 332 (21 residues), see Phobius details amino acids 338 to 363 (26 residues), see Phobius details amino acids 378 to 399 (22 residues), see Phobius details amino acids 405 to 426 (22 residues), see Phobius details PF00083: Sugar_tr" amino acids 25 to 226 (202 residues), 81.7 bits, see alignment E=5.4e-27 amino acids 240 to 422 (183 residues), 36.3 bits, see alignment E=3.2e-13 PF07690: MFS_1" amino acids 35 to 390 (356 residues), 116.4 bits, see alignment E=1.4e-37

Best Hits

KEGG orthology group: K03762, MFS transporter, MHS family, proline/betaine transporter (inferred from 85% identity to reh:H16_B1506)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YDN9 at UniProt or InterPro

Protein Sequence (444 amino acids)

>RR42_RS17750 MFS transporter (Cupriavidus basilensis FW507-4G11)
MHASAHPEAPSKPPSVSGAQRRHAIVATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDL
SSLLLAVATFGVGFFMRPVGGIILGVYADRVGRKAALSLTILLMALGTTMIGLAPTYGQI
GVVAPLLIVVARLLQGFSAGGEMGGATAFLTEYAPVERRAYYSSWIQASIGVAVLLGAAV
GTFVTSALSTEALNSWGWRLPFLLGIVIGPVGYYIRHHLDETPTFRDATDKSDSPLTEVL
RDYPRQTAASFSMVILWTVCTYVLLFYMPTYSVKVLHVPQSTGFIAGMVGGLAIMVCSPL
VGLLADRIGRRVLLSGSALLILVLAYPMFAYINQAPGLASLVVFQLVFGILIATYTGPIL
AAFSELFPAKVLSTGLSVAYNLAVTIFGGFASFIITWLIASTGSAMAPAFYVMFAAAISL
AGTRLVREPAYLRPAQATRATQPV