Protein Info for RR42_RS17410 in Cupriavidus basilensis FW507-4G11

Annotation: preprotein translocase subunit SecD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 623 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details transmembrane" amino acids 448 to 467 (20 residues), see Phobius details amino acids 471 to 490 (20 residues), see Phobius details amino acids 495 to 515 (21 residues), see Phobius details amino acids 540 to 562 (23 residues), see Phobius details amino acids 568 to 592 (25 residues), see Phobius details PF13721: SecD-TM1" amino acids 1 to 112 (112 residues), 114.6 bits, see alignment E=7.1e-37 PF07549: Sec_GG" amino acids 127 to 148 (22 residues), 24.7 bits, see alignment (E = 3.1e-09) TIGR01129: protein-export membrane protein SecD" amino acids 132 to 592 (461 residues), 447.7 bits, see alignment E=4.2e-138 PF21760: SecD_1st" amino acids 234 to 292 (59 residues), 94.7 bits, see alignment 4.4e-31 TIGR00916: protein-export membrane protein, SecD/SecF family" amino acids 352 to 585 (234 residues), 232.1 bits, see alignment E=6.6e-73 PF02355: SecD_SecF" amino acids 424 to 596 (173 residues), 78.3 bits, see alignment E=1.3e-25 PF03176: MMPL" amino acids 460 to 588 (129 residues), 32.3 bits, see alignment E=1.3e-11

Best Hits

KEGG orthology group: K03072, preprotein translocase subunit SecD (inferred from 93% identity to reu:Reut_A2810)

Predicted SEED Role

"Protein-export membrane protein SecD (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YDQ3 at UniProt or InterPro

Protein Sequence (623 amino acids)

>RR42_RS17410 preprotein translocase subunit SecD (Cupriavidus basilensis FW507-4G11)
MNRYPLWKYLVILVALAIGITYTLPNFFGEAPAVQVSSAKATVKVDLAMQKQIEQVLAQN
NLQPDGMFFDLNGQSGSVKARFKTPDEQLKAKDVLTRALNPDPNDATYVVALNLLSGSPR
WLTAMHALPMYLGLDLRGGVHFLLQVDMKGAVDKKLDSLAGDARTLLRDKGIRHGGIDRD
GDRLTVRFNNADDATKARGILADNLRELAFSPDGNNISGVFTDAARKAVQDAAVKQNITT
LHNRVNELGVAEPVIQQQGADRIVVQLPGVQDTAKAKDIIGRTATLEARLADPDAPRNPR
PGDPIPFGSELFTQGNGAPVVLKKQVIFTGDRIESASAGFDQNQRASVNIKLDAQGGRVL
RDVSRENIGKPMGIVLFEKGKGEVLTVATIQSELGSSFQITGSYSTEAANDLALLLRAGS
LAAPMEIIEERTIGPSLGADNIKKGFDSVAYGFGAIAVFMMLYYMLFGVFSVAALAINLL
LLVAVLSMLQATLTLPGIAAIALVLGMAIDANVLINERIREELRAGASPQMAIAVGFDRA
WATILDSNVTTLIAGLALLAFGSGPVRGFAVVHCLGIMTSMFSAVFFNRGLVNLWYGRKK
KLQSVAIGQIWKPGSDSQGTVAK