Protein Info for RR42_RS17380 in Cupriavidus basilensis FW507-4G11

Annotation: catalase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00199: Catalase
  • amino acids 9 to 389 (381 residues), 653.1 bits, E=1.6e-200
• PF06628: Catalase-rel
  • amino acids 419 to 478 (60 residues), 70 bits, E=1.6e-23

Best Hits

Swiss-Prot: 77% identical to CATA_BORPE: Catalase (katA) from Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 94% identity to reh:H16_A3109)

MetaCyc: 54% identical to catalase monomer (Homo sapiens)
Catalase. [EC: 1.11.1.21, 1.11.1.6]; 1.11.1.6 [EC: 1.11.1.21, 1.11.1.6]

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• ethanol degradation IV (3/3 steps found)
• superoxide radicals degradation (2/2 steps found)
• methanol oxidation to formaldehyde IV (1/2 steps found)

KEGG Metabolic Maps

• Methane metabolism
• Tryptophan metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.21 or 1.11.1.6

Sequence Analysis Tools

See A0A0C4YDC8 at UniProt or InterPro

Protein Sequence (481 amino acids)

>RR42_RS17380 catalase (Cupriavidus basilensis FW507-4G11)
MSKNKDTLTTAAGAPVADNQNSQTAGPRGPMLLQDVWFLEKLAHFDREVIPERRVHAKGS
GAHGKFTLTHDISRFTKASVFASVGKETPIFIRFSTVAGERGAADAERDVRGFSVKFYTD
EGNWDVVGNNTPVFFVRDPLKFPDFIHTQKRNPRTNLRDPIAVWDFWSRHPESLHQVTIL
MSDRGLPQNYRQIHGFGSHTFSFINAANERFWVKFHFKSQQGIANWTNEEAAKVVAGDRE
SAQRDLFENIERGNFPRWNVRVQVMPEADAAKYHINPFDLTKVWPHKDYPLIDVGVLELN
RNPDNYFAEVEQVAMNPSNIVPGIGFSPDKMLQGRLFSYGDTQRYRLGVNHNQIPVNAPK
CPFHNTFHRDGAMRVDGNQGGKLNYEPNREGAYAASERAIEPPLALDGAADRFDHRVDSD
DYSQPGALFRLFDEGQRQRLYANIAAAMQGVPESIVRAQLEHFTKADPAYGEGVKRALDL
K