Protein Info for RR42_RS16180 in Cupriavidus basilensis FW507-4G11

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF03401: TctC" amino acids 52 to 324 (273 residues), 302.3 bits, see alignment E=1.4e-94

Best Hits

Swiss-Prot: 40% identical to BUGT_BORPE: Protein BugT (bugT) from Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)

KEGG orthology group: None (inferred from 87% identity to reh:H16_A2980)

Predicted SEED Role

"Tricarboxylate transport protein TctC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YFE6 at UniProt or InterPro

Protein Sequence (328 amino acids)

>RR42_RS16180 ABC transporter substrate-binding protein (Cupriavidus basilensis FW507-4G11)
MNRRQFQLAGLACALGAGLGAVAPVAQADTWPSKPITVIVPFPAGGGTDAFARPLTAQLS
KQLGKQFVIDNRGGAGGTVGASIAAKGAPDGYTVFIGGAHHAIAPSFYKKLDYDIEKDFI
PITVIAQPPQVIVVNPAKVSASTLGELIAYAKKNPGKLNYASAGNGSSHHLAGELFKLQT
KTFITHIPYKGAGPALSDLIAGQVDMDFDGLGSSAQHIRAGRIKALAVASTKRSAAFPNV
PTAAEAGVPNYEVSTWYAMWVPKGTPKDIVDRLYTEVEKALNTPEIKQIWLANGSDTPAF
TQEQFAQFQHAEIKRWATVVQQSGAKID