Protein Info for RR42_RS16130 in Cupriavidus basilensis FW507-4G11

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00005: ABC_tran" amino acids 29 to 178 (150 residues), 99 bits, see alignment E=3.6e-32

Best Hits

Swiss-Prot: 42% identical to HMUV_STRCO: Hemin import ATP-binding protein HmuV (hmuV) from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

KEGG orthology group: K02013, iron complex transport system ATP-binding protein [EC: 3.6.3.34] (inferred from 73% identity to reu:Reut_A0656)

MetaCyc: 37% identical to iron(III) hydroxamate ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-11-RXN [EC: 7.2.2.16]; TRANS-RXN-297 [EC: 7.2.2.16]; TRANS-RXN-298 [EC: 7.2.2.16]

Predicted SEED Role

"Iron(III) dicitrate transport ATP-binding protein fecE"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.34 or 7.2.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YFE1 at UniProt or InterPro

Protein Sequence (278 amino acids)

>RR42_RS16130 ABC transporter ATP-binding protein (Cupriavidus basilensis FW507-4G11)
MPTWNEPVCACPSLVLQSLQLRAGARALLDGLSLSMQAGELWCVVGPNGVGKSTLMSVLA
GLRKPDGGVVLLDGRAPLETPPAALALRRAYLPQAVHDTFSMSVRDAVAVGRHPHLSGWG
WAGREDDAVVAAVMREMDLDALAGRDVLTLSGGERQRVSLAATLAQQAPLLMLDEPAAHL
DLRHQIMVLETLARLTRAGRHAIVVILHDLNLARRYATHALLLAEDGLCLHGPAAQVLTP
AHCSHALRTPIVSVSDGRHTALIADGAPSPAPDETQHD