Protein Info for RR42_RS13965 in Cupriavidus basilensis FW507-4G11

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF00126: HTH_1" amino acids 10 to 69 (60 residues), 65.9 bits, see alignment E=2.6e-22 PF03466: LysR_substrate" amino acids 95 to 295 (201 residues), 152.7 bits, see alignment E=9.1e-49

Best Hits

Swiss-Prot: 49% identical to YEIE_ECO57: Uncharacterized HTH-type transcriptional regulator YeiE (yeiE) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 83% identity to reh:H16_A2541)

Predicted SEED Role

"LysR family transcriptional regulator YeiE" in subsystem YeiH

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YHQ4 at UniProt or InterPro

Protein Sequence (301 amino acids)

>RR42_RS13965 LysR family transcriptional regulator (Cupriavidus basilensis FW507-4G11)
MSHRPLRLTLRQLSVFVAVAQHGSTVAAADALAMSQSAVSAALADLEATLGGSLFDRVAR
RLSINETGRLFFPRALSLLDQAQELERFTVQPGVQLRIAASNTIGSYILPGLLAGFRHAQ
SGPCALDMRIGNTREVLQALLHFEADIGLIEGTCHERDLRSAHWRDDVMVVVVSPSHPLA
SYPGNLAALRDADWVVREPGSGTREIIEQRLAPLLGELRFALELGNSEAIKRAVMSGYGV
SCLSLQVVEDELQRGTLVALRDGLPDVVRPLHLVVHQDKYPTQGLLAFTEYLRRDAAATS
Q