Protein Info for RR42_RS13565 in Cupriavidus basilensis FW507-4G11

Annotation: lytic transglycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 563 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01464: SLT" amino acids 124 to 227 (104 residues), 95.7 bits, see alignment E=1.4e-31 PF01476: LysM" amino acids 351 to 390 (40 residues), 15.7 bits, see alignment 1.2e-06 amino acids 428 to 463 (36 residues), 28.7 bits, see alignment 1e-10

Best Hits

KEGG orthology group: K08307, membrane-bound lytic murein transglycosylase D [EC: 3.2.1.-] (inferred from 86% identity to reh:H16_A2463)

Predicted SEED Role

"Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-)" (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YB48 at UniProt or InterPro

Protein Sequence (563 amino acids)

>RR42_RS13565 lytic transglycosylase (Cupriavidus basilensis FW507-4G11)
MKIGRLLAVVACAALLAACASTPTPPEGADGATATASASRPAISKPDPLNSINSAGVINV
DRDSMDWLRGPSSDIWDRIRRGFGMPDLEGTLVDDRTQWYAQRPEYMERMVGRSSRYLYH
IVEELERRKMPTELALLPFVESAFNPQAESTAKAAGMWQFIPSTGKSYNLKQNMFRDERR
DVLASTDAALDYLQRLYDMFGDWQLALAAYNWGEGAVSRAIARNQARGLPTDYASLNMPN
ETRYYVPKLQAVKNIIANPQMYGVKLPDIPDHPYFVTVTTSRDIDVKLAAKLANLPLDEF
KALNPSFNRPVILGAANPQILLPFDNAERFQYNLNTYRGGLSSWTAVTVDNRERIEALAA
RLNIDADTIREINRIPKGMRLKAGSTVVVPRSEDRNQDISATLAESATMAMEPDVPDARR
VVVRAGRRDTVATLAHRYGVSAGQVQSWNKLSGTKLVAGQSLVLMVPARSAARFASAPDP
APTASALVPVRAEPVRGSAKGRAAPRQRVTVEAAPRKGAAATARSSAKPAPTVSAAKASA
KPASAKAASKSAAGPAKTKAHAR