Protein Info for RR42_RS13380 in Cupriavidus basilensis FW507-4G11

Annotation: microcin ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 transmembrane" amino acids 9 to 30 (22 residues), see Phobius details amino acids 120 to 140 (21 residues), see Phobius details amino acids 155 to 182 (28 residues), see Phobius details amino acids 208 to 231 (24 residues), see Phobius details amino acids 266 to 289 (24 residues), see Phobius details amino acids 313 to 332 (20 residues), see Phobius details PF00528: BPD_transp_1" amino acids 136 to 343 (208 residues), 120.3 bits, see alignment E=4.1e-39

Best Hits

Swiss-Prot: 58% identical to YEJB_ECO57: Inner membrane ABC transporter permease protein YejB (yejB) from Escherichia coli O157:H7

KEGG orthology group: K13894, microcin C transport system permease protein (inferred from 95% identity to reu:Reut_A2128)

MetaCyc: 58% identical to putative oligopeptide ABC transporter membrane subunit YejB (Escherichia coli K-12 substr. MG1655)
3.6.3.23-RXN [EC: 7.4.2.6]

Predicted SEED Role

"Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YHD7 at UniProt or InterPro

Protein Sequence (350 amino acids)

>RR42_RS13380 microcin ABC transporter permease (Cupriavidus basilensis FW507-4G11)
MLAYLLKRVLLMIPTLLGVITLTFAVIQFVPGGPVEQMMLELKGRGGGGGEASGGGAEYR
GRRGVDPDKIKEIQALYGFDKPPLERYFMMLKRFARFDLGQSYFQHRSVWELVKSKMPVS
VSLGLWTFFLTYLISVPLGISKAIRAGSRFDVVTSMVVLVGYAIPGFVLGVLLLVLFGGG
TFVQWFPLRGLTSDNWDQLTLMGKVMDYLWHLVLPITASVVGSFAVVTMLTKNAFLEEIR
KQYVLTARAKGLAERRVLWKHVFRNALIPLVTGFPAAFIGAFFTGSLLIETLFSLDGLGL
LSYEAVLRRDYPVVLGTLYLFTLIGLVTRLISDVCYVMVDPRIHFEAVHR