Protein Info for RR42_RS12895 in Cupriavidus basilensis FW507-4G11
Annotation: cytochrome oxidase subunit III
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 49% identical to CCOP_RUBGE: Cbb3-type cytochrome c oxidase subunit CcoP (ccoP) from Rubrivivax gelatinosus
KEGG orthology group: K00406, cb-type cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 87% identity to reu:Reut_A2038)Predicted SEED Role
"Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)
MetaCyc Pathways
- arsenite to oxygen electron transfer (2/2 steps found)
- aerobic respiration I (cytochrome c) (3/4 steps found)
- aerobic respiration II (cytochrome c) (yeast) (3/4 steps found)
- arsenite to oxygen electron transfer (via azurin) (2/3 steps found)
- Fe(II) oxidation (2/6 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.9.3.1
Use Curated BLAST to search for 1.9.3.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0C4YAN4 at UniProt or InterPro
Protein Sequence (308 amino acids)
>RR42_RS12895 cytochrome oxidase subunit III (Cupriavidus basilensis FW507-4G11) MSDFFTDFWSYYIAAIALVGIVWCVWLLFSQRKVTKVVGAPEDTGHVWDGDLRELNNPLP RWWMWMFLLACIFGLGYLVLYPGLGSYAGVLKTSSRVELEAHRQAAEQLQREVYGKYMQM DVKQVAAEPAAREIGQRLFLNYCAQCHGSDARGSRGFPNLTDNDWLYGGDPETITQTITK GRNGVMPSFASTIDGKLAGDVAQYVRSLSGLSSDPIRASRGESTFKSTCAACHGSTGKGN QALGAPNLSDRVWLYGSSEANIVDAILKGHNNHMPAHEEILTPERIRMLTAYVWGLSNIG GAGEGGKQ