Protein Info for RR42_RS12820 in Cupriavidus basilensis FW507-4G11

Annotation: RND transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 506 signal peptide" amino acids 1 to 59 (59 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 30 to 486 (457 residues), 499 bits, see alignment E=6.9e-154 PF02321: OEP" amino acids 85 to 275 (191 residues), 75.6 bits, see alignment E=2.2e-25 amino acids 308 to 484 (177 residues), 82.4 bits, see alignment E=2e-27

Best Hits

KEGG orthology group: None (inferred from 81% identity to reh:H16_A2296)

Predicted SEED Role

"Outer membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y3Y2 at UniProt or InterPro

Protein Sequence (506 amino acids)

>RR42_RS12820 RND transporter (Cupriavidus basilensis FW507-4G11)
MNQALSSFSALSPRTRAACRRAGTLALTALAAAVLAGCAAFGNSHSTQTVTAPASLASAQ
ALPSQHGQWPSLDWVDQFKDPQLRALVDEAVKDSPNLQAAFARVEASRAMADATRSALYP
HVDFDGSLVRQRFSQTDLFEGTPLAGSWQNQSRLQAGLSYDFDFWGKNRKALEAALSDDR
AAEAESQASRLILTTSVARTYARLAALYAQRDVAERAIAQRRGLSDLSRDRLNAGLDTQV
ETTQARGTVASAQTDLLRVDEDILLARNQLAALLGKGPDRGLAIQRPTILAQSTPLLPDN
LTIDLLGRRPDLVAARWRVEATSKDIEVARTQFLPAVTLSAFAGVASLDPSNLLMGISRT
FGIGPAIRLPIFEGGKLRANLKGKYAQYDLAVANYNQTLVDALRETADTVASIRSVDTQI
TAQREALALAERAYSLSTIRYKAGLGTQLTVLNAESNVLQQRRLATDLQARRLDLQMGLI
KALGGGYQEQAEGAGTDAQKPAEARG