Protein Info for RR42_RS12405 in Cupriavidus basilensis FW507-4G11

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 PF00072: Response_reg" amino acids 12 to 128 (117 residues), 34 bits, see alignment E=2.8e-12 PF00563: EAL" amino acids 175 to 414 (240 residues), 98.6 bits, see alignment E=3.9e-32

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y3R8 at UniProt or InterPro

Protein Sequence (415 amino acids)

>RR42_RS12405 hypothetical protein (Cupriavidus basilensis FW507-4G11)
MNPSLSMPAWQVLLVDDDPDVHEITRLVLTDLTFSGRKIQFHSVYSGQACRAHLAAHPDT
ALVLLDVVMETDDAGLATVRYIREQLRNPDLQIVLRTGHPGMAPEREVVTGYEINGYFLK
TEMTAQKLTSVVIGGLRAYQYVKALQQSHGLPQPVPRAPELPTSEAGSDAQVEAAIEQAL
YSGQYRLQAVSQFDLGCAAIAAIALLPAWPGPTGWMPHAEIANHVRSPSLIGAINAALLR
RACELALAWHTDPQAALSSPARVSVPILLPLMAGAEESELLALPELLRQYLRETAQAGNV
LDLQLPGSLLGTATEAARLACARIQEQGASVTLADVGDTPISLANLQRLLPDRLQIPQGY
VRNVATDAKRAAIARAVIALAHTLGMQALANGLASSEELQFFKWEGCDIGQGDVL