Protein Info for RR42_RS12385 in Cupriavidus basilensis FW507-4G11

Annotation: formamidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03069: FmdA_AmdA
  • amino acids 7 to 384 (378 residues), 602.1 bits, E=1.9e-185

Best Hits

Swiss-Prot: 71% identical to FMDA_METME: Formamidase (fmdA) from Methylophilus methylotrophus

KEGG orthology group: K01455, formamidase [EC: 3.5.1.49] (inferred from 86% identity to bxe:Bxe_B1706)

MetaCyc: 55% identical to formamidase subunit (Paracoccidioides brasiliensis)
Formamidase. [EC: 3.5.1.49]

Predicted SEED Role

"Formamidase (EC 3.5.1.49)" (EC 3.5.1.49)

MetaCyc Pathways

• cyanide detoxification II (1/2 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Nitrogen metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.49

Sequence Analysis Tools

See A0A0C4YAD8 at UniProt or InterPro

Protein Sequence (410 amino acids)

>RR42_RS12385 formamidase (Cupriavidus basilensis FW507-4G11)
MADTLIKVDLAQSAYENEQVHNRWHPDIPMACWVNPGDEFILETYDWTGGFIKNNESADD
VRDIDLSIVHFLSGPVGVRGVKPGDLLVVDLLDVGAKPESQWGFNGFFSKQNGGGFLTDH
FPLAQKSIWDFHGVYTTSRHVPGVEFAGLIHPGLIGCLPDPKLLHTWNERETGLIKTDPN
RVPPLANPPFAATAHMGKLVGDAGRRAAAEGARTVPPREHGGNCDIKDLSRGSKVYFPVY
VDGAGLSVGDLHFSQGDGEITFCGAIEMAGWVHMRVNVIKDGMAKYGIKNPIFKPSPITP
TYNDYLIFEGISVDEQGKQHYLDVNVAYRQACLNAIEYLTKFGYSRAQAYAILGTAPVQG
HISGVVDIPNSCATLWIPTQIFDFDIRPQANGPTVHIKGGADVLLSQDVA