Protein Info for RR42_RS11630 in Cupriavidus basilensis FW507-4G11

Annotation: magnesium ABC transporter ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 860 transmembrane" amino acids 60 to 78 (19 residues), see Phobius details amino acids 83 to 100 (18 residues), see Phobius details amino acids 249 to 268 (20 residues), see Phobius details amino acids 279 to 303 (25 residues), see Phobius details amino acids 729 to 753 (25 residues), see Phobius details amino acids 765 to 783 (19 residues), see Phobius details amino acids 795 to 815 (21 residues), see Phobius details amino acids 830 to 850 (21 residues), see Phobius details TIGR01524: magnesium-translocating P-type ATPase" amino acids 4 to 857 (854 residues), 1106.9 bits, see alignment E=0 PF00690: Cation_ATPase_N" amino acids 12 to 75 (64 residues), 46.9 bits, see alignment 4.3e-16 PF00122: E1-E2_ATPase" amino acids 135 to 312 (178 residues), 133.6 bits, see alignment E=1.5e-42 TIGR01494: HAD ATPase, P-type, family IC" amino acids 223 to 370 (148 residues), 78.5 bits, see alignment E=3.8e-26 amino acids 569 to 689 (121 residues), 85.4 bits, see alignment E=3e-28 PF00702: Hydrolase" amino acids 330 to 615 (286 residues), 52.3 bits, see alignment E=2.5e-17 PF13246: Cation_ATPase" amino acids 389 to 439 (51 residues), 31.1 bits, see alignment 4.9e-11 PF00689: Cation_ATPase_C" amino acids 684 to 846 (163 residues), 72.9 bits, see alignment E=7.1e-24

Best Hits

Swiss-Prot: 55% identical to ATMA_ECOLI: Magnesium-transporting ATPase, P-type 1 (mgtA) from Escherichia coli (strain K12)

KEGG orthology group: K01531, Mg2+-importing ATPase [EC: 3.6.3.2] (inferred from 66% identity to reu:Reut_A1214)

Predicted SEED Role

"Mg(2+) transport ATPase, P-type (EC 3.6.3.2)" (EC 3.6.3.2)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.2

Use Curated BLAST to search for 3.6.3.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y3G6 at UniProt or InterPro

Protein Sequence (860 amino acids)

>RR42_RS11630 magnesium ABC transporter ATPase (Cupriavidus basilensis FW507-4G11)
MPDALLRAAGLPQATLLQQLDTSLEGLTGAEATLRLQNLGPNLVEHERPRPAVLDLLRRL
LNPLNVMLLTLAAVSSAIRDYDAAAVIALMVMLSVGLATVQERRSGRAAAALRAMVHTTA
ATQRRSQPGALPITSELPIGALVPGDIVHLAAGDLVPADARLLASKDLFVNQSALTGESL
PVEKFALESASGDEPGTLENIVLMGTAVASGSATVVVVLTGPRAVFGGIARSLSEETSGT
VFEQGLQRFARLMIGLIVILAPLVFLINGLTKGDWLEALLFAVAVAVGLTPEMLPMLVTV
NLAKGALAMSRRKVIVKHLSAIQNLGAMDILCTDKTGTLTQDRIILKKHVDLAGQETARV
LEFAYLNSYHQSGLHNLLDKAVLLHDEVGETLRLEGGYRKIDEVPFDFERRRMSVVVDGP
HGRLLVCKGAVEEVYAACASAELGGRAMALDDSHRHSLMSVCNALNEDGFRVIAIAYKPL
PPAPDTQPYSVADESALILLGYIAFIDPPKDSAAPALAALRDSGIEVKVLTGDSPVIARK
ICREVGLDVGRAVLGAELDGLTPQALGELAERTQLFAKLAPAHKAAIVKALRGRGRVVGV
LGDGINDGPALNAADVGISVDSGADIAKESASIILLEKSLLVLHDGVIEGRKVFANLLKY
LRMGASSNFGNMFSVLGASAWLPFLPMAPIQVLTNNLLYDFSQTALPTDNVDDDAVSRPR
RWEIGKLGRYILCIGPISSLFDYVTFATLYWILGASTPAQQHLFQTGWFLESLLSQTLIV
HVIRTRHVPFVQSRGSTALIATTLAICLIGIWLPYSPLAQPLGLLPPPGMLWLFLPPIIL
GYCCLTYALRGWLIGRFSID