Protein Info for RR42_RS11610 in Cupriavidus basilensis FW507-4G11

Annotation: serine hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 763 PF00144: Beta-lactamase" amino acids 21 to 350 (330 residues), 225.4 bits, see alignment E=1.7e-70 PF07075: NamZ_N" amino acids 412 to 612 (201 residues), 231.9 bits, see alignment E=7.4e-73 PF20732: NamZ_C" amino acids 617 to 763 (147 residues), 109.7 bits, see alignment E=3.5e-35

Best Hits

KEGG orthology group: None (inferred from 60% identity to bpy:Bphyt_5607)

Predicted SEED Role

"alternate gene name: yzbB" in subsystem Folate Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y9Y7 at UniProt or InterPro

Protein Sequence (763 amino acids)

>RR42_RS11610 serine hydrolase (Cupriavidus basilensis FW507-4G11)
MEATSLARTDAGTREQLRIIVAGQIEAGNVPGAVVLAGDAEHIHYRAAAGLRAVLPASEA
MLANTVFDLASVTKVIATTTAVLQLNERGSILLDAPVAQYLPEFGVAGKERVTVRELLSH
TSGLPAGLPPGRRSGGVNDIVREAMRQAPIAPPGSRVIYSDINFIVLGELVRRVSGQSLD
AWCREQIFTPLRMQDTGFLPGPAAARRIAPTASRGGEMLRGRVHDPIAARMGGVAGHAGL
FSTAEDLARFAQMILNDGRSGAATVLKPESVALLAAPASPLAANAWRGLGWALAAPLVAN
RDRLPALGMIEQTGYTGTGVWIDLVTKRFAVILSSRLHPYDRGDAAPLRQQVLALLASEA
APVAMAAITHAVPGTEVALAQAMRLPPAAGPVRSGIDVLEAQAFAPLSGLRVGLVTNRSG
FDSRGVRTADALAHAPGVTLAALFAPEHGLASDIDAPLGDSSDPATGVPVHSLYDGNKRF
APAALEGVDALVFDVQDAGVRFFTYITTLGYTLEAAAARGIPVFVLDRPNPLGADVFGGP
LQDPGTPSSFTGYFPLPLVHGMTVGELARMFNARLHIGADLRVVAMQGYIRHMRFSDTGL
GWVPISPNLRNTEQLELYPDLGMIEGANVSVGRGTPTPFELVGAPWIAGRDLADYLKKLD
TKARFEVTSFVPTEGRYRGRLCHGVSIKAAIGNTPPGRLGLALAIALHALYPRQFNLPAI
RASLGSERVWRLIDAHASLAAVEMAVSTQGADFAQDRARFLMY