Protein Info for RR42_RS11490 in Cupriavidus basilensis FW507-4G11

Annotation: MBL fold metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 313 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details TIGR04558: quinoprotein relay system zinc metallohydrolase 1" amino acids 25 to 311 (287 residues), 407.3 bits, see alignment E=1.5e-126 PF00753: Lactamase_B" amino acids 53 to 226 (174 residues), 34.6 bits, see alignment E=9.8e-13

Best Hits

KEGG orthology group: None (inferred from 77% identity to reh:H16_B1046)

Predicted SEED Role

"SoxH protein, homolog" in subsystem Sulfur oxidation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y3F0 at UniProt or InterPro

Protein Sequence (313 amino acids)

>RR42_RS11490 MBL fold metallo-hydrolase (Cupriavidus basilensis FW507-4G11)
MKRVLGILLWLAAQAALAQAGDAGDYRLAPRQVAADVWLLEGANADFAPDNGCNIINTAF
IDTGDGVVVINTGPSRQYGEQQRRAIASVTAAPVRLVFNLNLHPDYFFGNQAYADVGASA
LAGTIDGARREGPAYADNLYRLCGNWMRDTEPAPPRHVLTPGRRTIGRHTFDLVRMDGHT
ADDLVIVDRSAGIVFAGGVAFRERVPTTPHADLKRWLASLDQLQALLRDSGARLLIPSHG
PALGSADAIAQTRGYLQWLDARMTQAASQGRDLAEVIAMPVPQAYAHWGAMPAEYLRNVT
HLYPAYEDAALGR