Protein Info for RR42_RS11320 in Cupriavidus basilensis FW507-4G11

Annotation: molybdenum cofactor sulfurase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF03473: MOSC" amino acids 53 to 172 (120 residues), 138.7 bits, see alignment E=9.4e-45 PF03475: YiiM_3-alpha" amino acids 182 to 224 (43 residues), 49.4 bits, see alignment 3.5e-17

Best Hits

Swiss-Prot: 42% identical to YFLK_BACSU: Uncharacterized protein YflK (yflK) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 76% identity to reu:Reut_A1839)

Predicted SEED Role

"Uncharacterized protein conserved in bacteria"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y9R2 at UniProt or InterPro

Protein Sequence (237 amino acids)

>RR42_RS11320 molybdenum cofactor sulfurase (Cupriavidus basilensis FW507-4G11)
MTMTGVSIPIGCVLLGTVRPFGPKGVPSGIDKQAVDGAVRVTVLGLAGDGQGDPRHHGGP
EKAIHHYAFDHYPAWREELSPLSTQAAEVLARPGAFGENVSTAGLTEADVCIGDRFRLGG
ALVEVSQARQPCWKLNHRFGHAGMARAVQQSLRTGWYYRVLEEGGLERGDSLVLVERPYP
DWSLQRLLHVLYVDRLDAGALCVMATLPALAENWRKLARQRLERREVEDMEPRLAGG