Protein Info for RR42_RS11190 in Cupriavidus basilensis FW507-4G11

Annotation: acyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 540 PF18158: AidB_N" amino acids 3 to 158 (156 residues), 191.9 bits, see alignment E=1.4e-60 PF02770: Acyl-CoA_dh_M" amino acids 172 to 270 (99 residues), 60.8 bits, see alignment E=2.4e-20 PF00441: Acyl-CoA_dh_1" amino acids 280 to 434 (155 residues), 122.2 bits, see alignment E=4.3e-39 PF08028: Acyl-CoA_dh_2" amino acids 303 to 417 (115 residues), 46.8 bits, see alignment E=7.3e-16

Best Hits

KEGG orthology group: None (inferred from 67% identity to ctt:CtCNB1_4792)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7

Use Curated BLAST to search for 1.3.8.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y9R3 at UniProt or InterPro

Protein Sequence (540 amino acids)

>RR42_RS11190 acyl-CoA dehydrogenase (Cupriavidus basilensis FW507-4G11)
MTNQVPELKDYNLYTSDPGIRRAVARAGAGWNEGELERQGAVLGAEQTIQHAEDANRHHP
ELHTHSRIGERIDQVRFHPAWHELMAMARHSGLANLPFADTRPSAWASYAASLYMHSQIE
SGSLCPTNMTQACIPVLRKEPGLFAQFGDKLLTQAYDPRDLPIAHKRSINVGMGMTEKQG
GSDVRANTTRAVPGRGEGRGAEYLITGHKWFFSAPMSDAHLVLANTEAGSSCFFVPRWRP
DGSKNPIEIQRLKDKVGNRSNSSSEVEFRDAWGIMVGEEGRGIPTILEMATYSRLNCSLS
SAGFLRQALVQALHYARHRSAFGKPLIRQPLMVRLLADMALEAEAAMLLAMDLATAFEAT
DDPARLAWRRILTPASKFWICKRAVEMTGEAMEVFGGNGYVEDGPMGRLFREAPVNSIWE
GSGNVMCLDVLRAIGRNPHDYLRVLEHMSVVGADEPRIQASVAALRAALRLPEEEQQAEA
RRTTTRLVLTAQACLMLQHADTATADAFLASRFDPEWGAVMGISAGQSHAARILEMAWAA