Protein Info for RR42_RS11025 in Cupriavidus basilensis FW507-4G11

Annotation: aspartate racemase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 236 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details TIGR00035: aspartate racemase" amino acids 1 to 231 (231 residues), 237.4 bits, see alignment E=8.1e-75 PF01177: Asp_Glu_race" amino acids 7 to 224 (218 residues), 143.7 bits, see alignment E=3.6e-46

Best Hits

Swiss-Prot: 52% identical to YGEA_ECO57: L-aspartate/glutamate-specific racemase (ygeA) from Escherichia coli O157:H7

KEGG orthology group: K01779, aspartate racemase [EC: 5.1.1.13] (inferred from 74% identity to rme:Rmet_4003)

MetaCyc: 52% identical to amino acid racemase YgeA (Escherichia coli K-12 substr. MG1655)
5.1.1.-

Predicted SEED Role

"Aspartate racemase (EC 5.1.1.13)" in subsystem Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 5.1.1.13)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 5.1.1.13

Use Curated BLAST to search for 5.1.1.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YBQ7 at UniProt or InterPro

Protein Sequence (236 amino acids)

>RR42_RS11025 aspartate racemase (Cupriavidus basilensis FW507-4G11)
MKTIGLIGGMSWESSAEYYRLINQDMKQRLGGHHNARSVMVTVSFEQIKALQHAQRWDEL
GEAMRQAALQVQAAGADFVLLCTNTMHRVAPVLEAALDIPFLHIVDPTAQALRAAGIRRV
ALLGTAFTMEQDFYRGRMQDKHGIEVVVPDAADRALVHAIIYDELCHGIVRDASRDVYRR
IIGGLQAQGVGGVILGCTEIALLIGQDDVALPVFDTTALHAQAAVGLALEGVVVAN