Protein Info for RR42_RS09485 in Cupriavidus basilensis FW507-4G11

Annotation: amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 216 transmembrane" amino acids 19 to 41 (23 residues), see Phobius details amino acids 52 to 75 (24 residues), see Phobius details amino acids 87 to 99 (13 residues), see Phobius details amino acids 183 to 203 (21 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 11 to 107 (97 residues), 99.8 bits, see alignment E=5.4e-33 PF00528: BPD_transp_1" amino acids 31 to 212 (182 residues), 83.1 bits, see alignment E=1.1e-27

Best Hits

Swiss-Prot: 38% identical to YECS_SHIFL: L-cystine transport system permease protein YecS (yecS) from Shigella flexneri

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 96% identity to reh:H16_B1809)

MetaCyc: 38% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

No annotation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y8J7 at UniProt or InterPro

Protein Sequence (216 amino acids)

>RR42_RS09485 amino acid ABC transporter permease (Cupriavidus basilensis FW507-4G11)
MITEFSWNHLEILLLAARWTLWVTLLAFVGGTLAGFLVALARTSRSALLRLASTVYIQIV
QGTPVLIVLFLSYYGLSVLGLKLSPMTAAMLAMSIYASAYLGEIWRGCIEAVPQGQWEAS
EALALTRWQQLRHVVLPQAVRLALPPTVGFSVQLVKNTSITSIIGVIELTRAGQLINNAT
FQPFAVFVVVALIYFALCFPLSSAARRMERRLHAHR