Protein Info for RR42_RS07830 in Cupriavidus basilensis FW507-4G11

Annotation: N-acyl-L-amino acid amidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 468 signal peptide" amino acids 1 to 43 (43 residues), see Phobius details TIGR01891: amidohydrolase" amino acids 68 to 449 (382 residues), 349.6 bits, see alignment E=1.1e-108 PF01546: Peptidase_M20" amino acids 126 to 458 (333 residues), 132.4 bits, see alignment E=2.1e-42 PF07687: M20_dimer" amino acids 258 to 351 (94 residues), 46.3 bits, see alignment E=3.7e-16

Best Hits

KEGG orthology group: K01436, amidohydrolase [EC: 3.5.1.-] (inferred from 87% identity to cti:RALTA_A1367)

Predicted SEED Role

"N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)" in subsystem Lysine Biosynthesis DAP Pathway (EC 3.5.1.47)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.-, 3.5.1.47

Use Curated BLAST to search for 3.5.1.- or 3.5.1.47

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y1K5 at UniProt or InterPro

Protein Sequence (468 amino acids)

>RR42_RS07830 N-acyl-L-amino acid amidohydrolase (Cupriavidus basilensis FW507-4G11)
MAAQQTHRSRTSTRATLSAGLSALSLAAGLLCLAPAPAAAAAAQAQATGSESLQAQIETR
AKAVEAQLIAWRRDIHQHPELGNYEVRTARLVADHLRKLGMEVTTGVAKTGVVGVLKGGK
PGPVVALRADMDAIPVKERVDVPFASKAKGQYLGKEVDVMHACGHDTHVAILMATAEVLA
GMKDQLPGTVKFIFQPAEESPADFEPNGSNMWGAKQMVAEGVLDNPKVDAIFGLHVTSNI
ESGKLGWRSGPAMAAADQFWIDVKGRQTHGARPWGGIDPIVVASQIVLGLQTIQSRQVDA
MLEPSVITVGTIHGGNRMNIVPEKVEMMGTIRTYDQGMKKDIHARMKRTTEAIAASAGAE
ADFKVLELYDATINQPALTEKMAPTLKRVAGDGNWMITPKATASEDFSFYQAKVPGLFFN
LGVTPKGTDVNKAPSNHSPEFYVDEAALVNGVRALAGLTVDYMTMAQR