Protein Info for RR42_RS04440 in Cupriavidus basilensis FW507-4G11

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00691: OmpA" amino acids 103 to 195 (93 residues), 72.5 bits, see alignment E=1.5e-24

Best Hits

Swiss-Prot: 52% identical to OMPA_BORAV: Outer membrane protein A (ompA) from Bordetella avium

KEGG orthology group: K03286, OmpA-OmpF porin, OOP family (inferred from 94% identity to rme:Rmet_0712)

Predicted SEED Role

"Outer membrane protein A precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y7Z9 at UniProt or InterPro

Protein Sequence (219 amino acids)

>RR42_RS04440 membrane protein (Cupriavidus basilensis FW507-4G11)
MKKFAKLALVAATAVMAASAQAQSVPYEKKAVNDSWGNGTSEYVWKNGTNELCWRDSSWT
PATANALCDGALAPAVAPAATQPPAAVPPVVSSEKVTFAADTLFDFDKAVLKPEGKAKLD
DLSSKLSGITLEVIIAVGHTDSFGSDKYNDRLSIRRAEAVKAYLVSKGVEANRVYTEGKG
KRQLKVDPKSCKGNRKAQIACQQPNRRVEVEVVGTRSAR