Protein Info for RR42_RS04395 in Cupriavidus basilensis FW507-4G11

Annotation: cysteine ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 265 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF00497: SBP_bac_3" amino acids 39 to 257 (219 residues), 224.8 bits, see alignment E=9.3e-71 PF10613: Lig_chan-Glu_bd" amino acids 63 to 131 (69 residues), 35.8 bits, see alignment E=7.6e-13

Best Hits

KEGG orthology group: K02030, polar amino acid transport system substrate-binding protein (inferred from 83% identity to cti:RALTA_A0759)

Predicted SEED Role

"Cystine ABC transporter, periplasmic cystine-binding protein FliY"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y5P5 at UniProt or InterPro

Protein Sequence (265 amino acids)

>RR42_RS04395 cysteine ABC transporter substrate-binding protein (Cupriavidus basilensis FW507-4G11)
MRSLRTGCLNALFAVSLLAAGAAAQAADLLDTVKQAGVLKIGLEGTYPPFNYRGSNNQLE
GFDVDVAKGVAAKLGVKPEFVTTEWSGIIAGLQAGKFDVIVNQVAVTPQRKQVLDFSTPY
VYSAAQLIQRKDDNRQFKSLEDLKGKKLGVSLGSNYNELAKSVAGIDVKTYPGAPEYLRD
LAAQRVDAALNDRLMIGYLIKTSNLPLRPGAIVEGGNSEVAIPFRKDNPKFAQAIDRALD
EMRKDGSLGKLSARWFGSDVTKPAR