Protein Info for RR42_RS04120 in Cupriavidus basilensis FW507-4G11

Annotation: pilus assembly protein TadG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 transmembrane" amino acids 16 to 37 (22 residues), see Phobius details PF13400: Tad" amino acids 16 to 63 (48 residues), 50.7 bits, see alignment 9e-18

Best Hits

KEGG orthology group: None (inferred from 68% identity to rme:Rmet_0645)

Predicted SEED Role

"Von Willebrand factor type A domain protein, associated with Flp pilus assembly" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y5U7 at UniProt or InterPro

Protein Sequence (426 amino acids)

>RR42_RS04120 pilus assembly protein TadG (Cupriavidus basilensis FW507-4G11)
MLRRTALSSHRARQRGAVAIIVAIALVMLVGFLGLALDLGKLYVAKSELQNGADSCALAA
ARDLTGATPLTVSEAAGITAGLRNMALFQSESVQLVANQSVTYSDALTDPFLDKNSVTYP
LASIKYVKCSVSRAGIANWFAQVLNFLPGVSVGPQTVASFAVATTGSAQTTCAIPVFVCK
PSTISPPQPPYTTGQWLVTKLDSSNKGTYGGGNFGWADLGGGNSASQIAKQLDGAGQCNL
PAQGTLIGSAGNKASLADDWNSRFGIVKGSKVLGVTDFTGFTYNDTTWTAKSSAYDGSSV
DTSGNTQPNFLAARKAYRAYQGDSVTGLSTQGNAAPAASYQSGADRRLVLAPIVDCSGFA
SPGNHSAPVQSWACLLMIEPMQTGGNIDSVRLEYRGDSSAPGSPCATQGIPGAGTGVGPL
VPVLVQ