Protein Info for RR42_RS03430 in Cupriavidus basilensis FW507-4G11

Annotation: SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF02353: CMAS" amino acids 24 to 147 (124 residues), 28.4 bits, see alignment E=5.8e-10 PF05175: MTS" amino acids 33 to 143 (111 residues), 30.5 bits, see alignment E=1.5e-10 PF01209: Ubie_methyltran" amino acids 36 to 146 (111 residues), 65.4 bits, see alignment E=2.8e-21 PF13489: Methyltransf_23" amino acids 36 to 187 (152 residues), 74.9 bits, see alignment E=3.4e-24 PF03848: TehB" amino acids 37 to 150 (114 residues), 34.6 bits, see alignment E=7.2e-12 PF00891: Methyltransf_2" amino acids 38 to 186 (149 residues), 26.8 bits, see alignment E=1.8e-09 PF07021: MetW" amino acids 39 to 134 (96 residues), 23.8 bits, see alignment E=1.7e-08 PF13847: Methyltransf_31" amino acids 42 to 185 (144 residues), 86.7 bits, see alignment E=8e-28 PF13649: Methyltransf_25" amino acids 45 to 138 (94 residues), 90.7 bits, see alignment E=4.3e-29 PF08242: Methyltransf_12" amino acids 46 to 139 (94 residues), 60.8 bits, see alignment E=1e-19 PF08241: Methyltransf_11" amino acids 46 to 142 (97 residues), 97 bits, see alignment E=4.6e-31

Best Hits

KEGG orthology group: None (inferred from 76% identity to cti:RALTA_A0556)

Predicted SEED Role

"SAM-dependent methyltransferase YafE (UbiE paralog)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y5H2 at UniProt or InterPro

Protein Sequence (252 amino acids)

>RR42_RS03430 SAM-dependent methyltransferase (Cupriavidus basilensis FW507-4G11)
MQQQELVAAQFGATASAYLTSAVHAQGADLQQLAQELAVLPAAQVLDLGCGAGHASFAAA
GVAAQVTAYDLSAEMLAVVQGAARDKGLANIRTRQGAAESLPFDDASFDAVISRMSAHHW
RNVPAALAQMYRVLKPGGKVVLIDIAGSDDPLPDTWLQSVELLRDPSHIRDYTGTEWKAM
LETAGFTASVSPAWRIELEFATWVQRMRTPPVAVAAIQHLWQLAPAEVRDHYLVKADGSF
ALEAVMVTATRG