Protein Info for RR42_RS02540 in Cupriavidus basilensis FW507-4G11

Annotation: taurine ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF09084: NMT1" amino acids 41 to 255 (215 residues), 127.6 bits, see alignment E=6.6e-41 PF04069: OpuAC" amino acids 55 to 249 (195 residues), 29.4 bits, see alignment E=6.3e-11

Best Hits

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 90% identity to reh:H16_A0467)

Predicted SEED Role

"Hydroxymethylpyrimidine ABC transporter, substrate-binding component" in subsystem Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YBH4 at UniProt or InterPro

Protein Sequence (340 amino acids)

>RR42_RS02540 taurine ABC transporter permease (Cupriavidus basilensis FW507-4G11)
MQLGMALGTALVLSTQFAGEAHAQTKVRFQLDWRFEGPSALFLLGEQKGYYKAEKLDVSI
DAGNGSGNVVNRVASGTYDMGFADLASVMEFYGNNPDAKNKPVAVMMVYNNTPAAVLALK
KSGIKTPHDLAGKKLGAPVFDAGRRAFPIFAKANGLQASSFNWQAMDPTLRETMLMRGDL
DAITGFSFTSILNLNARGVKDEDIVVLPYPQYGVKLYGNAVIASEDFLKKNPEAVKAFLR
AFAKSAKDVIAKPEEGIKAVKARDGIIDEKLETKRLKMALDSVVKSPDARAEGFGRINKP
RLSLMASQVADAFGTKGRINPDNLWTDAYLPSAAELDVLR