Protein Info for RR42_RS02380 in Cupriavidus basilensis FW507-4G11

Annotation: FAD-linked oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1324 PF12447: DUF3683" amino acids 19 to 143 (125 residues), 174.6 bits, see alignment E=2e-55 PF01565: FAD_binding_4" amino acids 193 to 338 (146 residues), 80.2 bits, see alignment E=3.9e-26 PF02913: FAD-oxidase_C" amino acids 461 to 576 (116 residues), 24.6 bits, see alignment E=5.8e-09 amino acids 728 to 815 (88 residues), 63.9 bits, see alignment 6e-21 PF13183: Fer4_8" amino acids 851 to 930 (80 residues), 33.7 bits, see alignment 1.3e-11 PF02754: CCG" amino acids 1061 to 1150 (90 residues), 27.6 bits, see alignment 7.7e-10 amino acids 1187 to 1277 (91 residues), 23.4 bits, see alignment 1.6e-08 PF11880: DUF3400" amino acids 1280 to 1324 (45 residues), 86.1 bits, see alignment (E = 2.8e-28)

Best Hits

Predicted SEED Role

"FAD/FMN-containing dehydrogenases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4XZE1 at UniProt or InterPro

Protein Sequence (1324 amino acids)

>RR42_RS02380 FAD-linked oxidase (Cupriavidus basilensis FW507-4G11)
MNAPLVLDAKLAAQDAPARLREIPYNYTSFSDREIVIRLLGEEAWRILAELRGERRTGRS
ARMLYEVLGDIWVVRRNPYLQDDLLENPKRRQMLVTALHHRLSEVEKRRAADRAEHAEPA
AEDRSHRVEQLVSFAKQAIEDFKQEFAHAYDLRKRTQRVLGRITQKDNIKFDGLSRVSHV
TDATDWRVEYPFVVLTPDTEEEIAGMVKGCFELGLTIIPRGGGTGYTGGAVPLTPMSAVI
NTEKLEQLGPVEQTDLPGVSHKVGTIFSGAGVVTRRVADAADKAGLVFAVDPTSIDASCI
GGNVAMNAGGKKAVLWGTALDNLAWWRMVDPEGNWLEVTRLDHNLGKIHDVAVATFELKW
SDGNRAPGEKPLRTETLAIEGRKFRKEGLGKDVTDKFLAGLPGIQKEGCDGIITSARWIL
HRMPAHVRTVCLEFFGQARDAIPSIVEIKDYLDAESRTPGGAILAGLEHLDERYLRAVGY
ATKSKRNAFPKMVLIGDIVGDDQDAVARATSEVIRMANGKSGEGFVAVSPEARKKFWLDR
SRTAAIARHTNAFKINEDVVIPLPRMGEYTDGIERINIELSIKNKLQLTDALEAFFARGN
LPLGRSDDANEIPSAELLEDRVQHALQLLREIRSRWTYLQDHLDTPLATARASLIGHGLG
LLGQAFEARLEQQPDATVFHLLQDRTIRVSWKSEVRAELRNIFNGGEFKPILDEAQKIHK
QVLRGRVFVALHMHAGDGNVHTNIPVNSDDYDMLQDAHRAVARIMALARSLDGVISGEHG
IGITKLEFLTEDEIGEFREYKQRVDPQGRFNKGKLLPGADLRNAYTPSFGLMGHESIIMQ
QSDIGAIADSVKDCLRCGKCKPVCATHVPRANLLYSPRNKILATSLLVEAFLYEEQTRRG
ISIKHWDEFSDVADHCTVCHKCVTPCPVKIDFGDVSMNMRNLLRKMGQKKFNPGTAASMF
FLNATNPQTINMTRKVMIDWGYKAQRLGNDVLKKFARKQTAHPPATVGRAPVQEQVIHFI
NKKMPGNLPKKTARALLDIEDNEIVPIIRDPKRTSPETEAVFYFPGCGSERLFSQVGLAT
QAMLWHVGVQTVLPPGYLCCGYPQRGNGQFDKAEKMVTDNRVLFHRVANTLNYLDIKTVV
VSCGTCYDQLAGYEFDKIFPGCRIIDIHEYLLEKGVKLEGVTGTRYMYHDPCHTPIKTMD
PTKLVNELMGGNEGGSKIEKNERCCGESGTLAVSRPDVSTQIRFRKEEEMTKGADKLRTD
GFVGDVKILTSCPSCLQGLSRYKEDATVTADYIVVEMAKHLLGENWMPDYVAKANSGGIE
RVLV