Protein Info for RR42_RS01980 in Cupriavidus basilensis FW507-4G11

Annotation: peptidase M16

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 508 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF00675: Peptidase_M16" amino acids 87 to 233 (147 residues), 88.8 bits, see alignment E=3.7e-29 PF05193: Peptidase_M16_C" amino acids 243 to 423 (181 residues), 107.2 bits, see alignment E=9.8e-35

Best Hits

KEGG orthology group: K01422, [EC: 3.4.99.-] (inferred from 81% identity to reh:H16_A0364)

Predicted SEED Role

"FIG015547: peptidase, M16 family"

Isozymes

Compare fitness of predicted isozymes for: 3.4.99.-

Use Curated BLAST to search for 3.4.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y4P9 at UniProt or InterPro

Protein Sequence (508 amino acids)

>RR42_RS01980 peptidase M16 (Cupriavidus basilensis FW507-4G11)
MNHCAVRSRSGAARTASLLAGAGAVRPAAFSRRLVPTLLLIAMPWFGAAYAQTAVVAPPL
PTGQATAAQTAAAQADTTEFTLSNGMRVIVKEDHRAPTVAHQIWYRVGGMDEVSGTTGVA
HMLEHMMFKGTPKVGPGEFSKQIAALGGRENAMTNRDFTLYYQQISKQYLPKMMELEADR
MANLIIKKDEFEREMKVVMEERRLRTDDSARGTVYEQLLATVYTAGPYRHPVIGWPADLV
NMRVEDVQAWYKNWYVPDNALLVVTGDVTAAEVKALAERTYGKLKARPLPLRKDQQEPAQ
KGIKRIWVKAPAENPYVVLAYKVPRLHDVEKDVDPYALEVLSAVLNGYDNARLTRDLVRE
RRIADDVNVGYDSINRGESLMVLDGTPATGHTTEEIERALRDEIARIAREGVSPAELKRV
KAQVVAAQIYKRDSVFGQGMEIGVAEIAGISWRQLDRMLDKIKAVTPEQVQAVAGKYFND
DNLTVATLLPQPIDPNKAKAPAAADSLR