Protein Info for RR42_RS01515 in Cupriavidus basilensis FW507-4G11

Annotation: cytidyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details PF01467: CTP_transf_like" amino acids 2 to 70 (69 residues), 46.9 bits, see alignment E=3.3e-16 TIGR00125: cytidyltransferase-like domain" amino acids 2 to 58 (57 residues), 44.6 bits, see alignment E=6.6e-16 PF00293: NUDIX" amino acids 204 to 327 (124 residues), 61.1 bits, see alignment E=1.1e-20

Best Hits

Predicted SEED Role

"Nicotinamide-nucleotide adenylyltransferase, NadM family (EC 2.7.7.1) / ADP-ribose pyrophosphatase (EC 3.6.1.13)" in subsystem NAD and NADP cofactor biosynthesis global or Nudix proteins (nucleoside triphosphate hydrolases) or NAD regulation (EC 2.7.7.1, EC 3.6.1.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.13

Use Curated BLAST to search for 2.7.7.1 or 3.6.1.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y4A3 at UniProt or InterPro

Protein Sequence (348 amino acids)

>RR42_RS01515 cytidyltransferase (Cupriavidus basilensis FW507-4G11)
MVYIGRFEPFHNGHFAMLRQALALASTVIVVLGSAGGARTVKNPFSADERRQMIQGAVAA
WDAARVADLRFVVVRDYYESARWTAAVRAVAGAAIEACAHGTPRVGLFGHFKDASSGYLN
DFPGWELVPQPSFGQLNAADVRRQWFEQQGGLEGLQSVLPQPVAAFLREFAGREAFATLL
AEYRFLQDHSRRWAAAPYAPVFVTVDAVVRCCGQVLLIRRGGQPGRGAWALPGGFLDQHE
RVADAVLRELDEETRFGLPKAALQQSLRDQALFDHPERSQRGRTLTHAFFFDLPLDALPA
VAAADDAAAVRWVPQQALLALEGQMFEDHLLILDRFLHLFDGEAQPAG