Protein Info for RR42_RS01335 in Cupriavidus basilensis FW507-4G11

Annotation: methylmalonyl-CoA carboxyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01039: Carboxyl_trans
  • amino acids 29 to 500 (472 residues), 292 bits, E=4.1e-91

Best Hits

KEGG orthology group: None (inferred from 84% identity to dia:Dtpsy_3419)

Predicted SEED Role

"Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)" in subsystem Serine-glyoxylate cycle (EC 6.4.1.3)

MetaCyc Pathways

• methylaspartate cycle (14/19 steps found)
• propanoyl CoA degradation I (2/3 steps found)
• superpathway of anaerobic energy metabolism (invertebrates) (12/17 steps found)
• 2-oxobutanoate degradation I (2/4 steps found)
• 3-hydroxypropanoate cycle (8/13 steps found)
• anaerobic energy metabolism (invertebrates, mitochondrial) (5/10 steps found)
• 3-hydroxypropanoate/4-hydroxybutanate cycle (10/18 steps found)
• superpathway of the 3-hydroxypropanoate cycle (10/18 steps found)
• superpathway of L-methionine salvage and degradation (7/16 steps found)
• mycolate biosynthesis (26/205 steps found)
• superpathway of mycolate biosynthesis (27/239 steps found)

KEGG Metabolic Maps

• Propanoate metabolism
• Valine, leucine and isoleucine degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.4.1.3

Sequence Analysis Tools

See A0A0C4Y4F4 at UniProt or InterPro

Protein Sequence (515 amino acids)

>RR42_RS01335 methylmalonyl-CoA carboxyltransferase (Cupriavidus basilensis FW507-4G11)
MSWQPEIDELAYRKQLAAQLGGPDKVKRHKDAGKLTVRERIDAIADAGSFREVGALTGSG
QYDSNGRLVGLTPANLVMGRAKVDGRPVVLVGDDFTVRGGANDGAVGEKLIHAEKMAHDL
RLPMVRLVDGTGGGGSVRNIENKGYTNIPTMKVWQHVVENMSLVPVVSLALGSVAGMGAA
RVAASHYSVMVKGTAQLFNAGPPVVARIGQVLEKNELGGSQIHTRNGVVDDEVASEEEAF
ARARRFLSYLPGSVHELPPRVEPTDDPARRDEWLLSAIPRDSRSVYKVRPIVETLVDQGS
FFEMGRHWGRAIVTGLARVDGWPVAVVASDPYHYGGGWDGPTAEKFIRFVDLAEAFHLPV
INMVDIAGFQIGLEAEKAGTMRYGVRALAAVYQATTPWCSVILRRAYGVAAAGHQHMGRF
NFRYAWPSGNWGSLPIEGGLEVAYKAEIEGADDPVQKRAEIEQRVRSLTSPFRSAEAFVV
EDIIDPRDTRSLLCEFANLAAPLREPGVRKFGIRP