Protein Info for RR42_RS01190 in Cupriavidus basilensis FW507-4G11

Annotation: peptidase M48

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF01435: Peptidase_M48" amino acids 105 to 267 (163 residues), 124.6 bits, see alignment E=2.2e-40

Best Hits

KEGG orthology group: None (inferred from 77% identity to reu:Reut_A0192)

Predicted SEED Role

"Zn-dependent protease with chaperone function"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y6F8 at UniProt or InterPro

Protein Sequence (315 amino acids)

>RR42_RS01190 peptidase M48 (Cupriavidus basilensis FW507-4G11)
MPRRLAALALAAGAALSMSAAEVQAQAQPQEAEDGIRVQRGGASIRQIVPVEVIEQQASQ
EYEQLKEEAQAKKTLVGDNNPQLVRLRAIAKRILPQTPRWNERAKQWKWEVNLINSKQVN
AFCMPGGKIAFYSGLLDQLKLTDEEVAMVMGHEIAHALQEHARERAAQSEITNLGANVIS
QLFGFGNLGNMALGTGAQLLTLRFSRSDETEADLVGMDIAARAGYDPRAAVSLWQKMGAV
SQSSAQSGSEFLSTHPSGRTRIAELEKHLPEVLPLYARAIDSSVGKLPPYRANMANLSGA
PVDSGDDDRQKPLKK