Protein Info for RR42_RS01180 in Cupriavidus basilensis FW507-4G11

Annotation: acyl-CoA thioesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 transmembrane" amino acids 38 to 51 (14 residues), see Phobius details PF13622: 4HBT_3" amino acids 32 to 114 (83 residues), 80.5 bits, see alignment E=1.3e-26 PF03061: 4HBT" amino acids 66 to 105 (40 residues), 23.7 bits, see alignment 7.5e-09 PF20789: 4HBT_3C" amino acids 137 to 273 (137 residues), 92 bits, see alignment E=6.3e-30

Best Hits

KEGG orthology group: None (inferred from 80% identity to reu:Reut_A0190)

Predicted SEED Role

"TesB-like acyl-CoA thioesterase 2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4XYU3 at UniProt or InterPro

Protein Sequence (276 amino acids)

>RR42_RS01180 acyl-CoA thioesterase (Cupriavidus basilensis FW507-4G11)
MSATPASQTIHSFDHAIALEPAGGNLFHGRTTPAYWNMIGPFGGITAATLLQAVLQHPER
LGDPSALTVNFAGPIVEGPFVIEARPVRTNRNTQHWTIELRQGDEVATTATAFFAVRRET
WNCGEAVFPQVPPASDVAPMAGFAPVRWLDAYELRPVRGAKPNVEAGTENPDSVTQFWLR
DAPARTPDFAAMAAWCDAFYPRIFLKRAGFVPAGTVSLTTYFHADAPTLAALGNSHVLGS
AQAQVFRQGFFDQSAQIWSPQGELLATSHQIVYYKQ