Protein Info for RR42_RS01155 in Cupriavidus basilensis FW507-4G11

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 PF00072: Response_reg" amino acids 7 to 116 (110 residues), 100.3 bits, see alignment E=7.6e-33 PF00486: Trans_reg_C" amino acids 155 to 230 (76 residues), 79.7 bits, see alignment E=1.4e-26

Best Hits

Swiss-Prot: 37% identical to CSEB_STRAW: Transcriptional regulatory protein CseB (cseB) from Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)

KEGG orthology group: K07663, two-component system, OmpR family, catabolic regulation response regulator CreB (inferred from 77% identity to rme:Rmet_1652)

Predicted SEED Role

"Two-component response regulator CreB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4XYU1 at UniProt or InterPro

Protein Sequence (232 amino acids)

>RR42_RS01155 transcriptional regulator (Cupriavidus basilensis FW507-4G11)
MTKPPSILVIEDESAIADTILYALSTEGMTVEHCALGSAALARLRAQAPDLVILDVGLPD
INGFEVCRTLRTFSDVPVIFLTARNEEIDRIVGLEIGADDYVVKPFSPRELAARVRVILR
RAGKRAAPQEPVQAPAPPEGFTLDADGARLAWRGQWLDLTRYEYRLLALLLQHPGRIYSR
AQLMDLVWHDALDTIDRTVDTHIKTVRAKLRALDPECDSIRTHRGMGYSLEG