Protein Info for RR42_RS01135 in Cupriavidus basilensis FW507-4G11

Annotation: dihydroorotate oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00440: TetR_N" amino acids 55 to 84 (30 residues), 33.9 bits, see alignment 1.1e-12

Best Hits

Swiss-Prot: 47% identical to SLMA_MARMS: Nucleoid occlusion factor SlmA (slmA) from Marinomonas sp. (strain MWYL1)

KEGG orthology group: K05501, TetR/AcrR family transcriptional regulator (inferred from 83% identity to rme:Rmet_0142)

Predicted SEED Role

"Transcriptional regulator SlmA, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y4C3 at UniProt or InterPro

Protein Sequence (219 amino acids)

>RR42_RS01135 dihydroorotate oxidase (Cupriavidus basilensis FW507-4G11)
MMHSNGHPSGAAPAAAGQGAGADGAPARKRPRPGERRVQILQTLAGMLEVPRGEKVTTAA
LAAKLSVSEAALYRHFASKAQMFEGLIGFIEQTVFGLINQITTQEEHGLRQAHAVVRMLL
SFAEKNPGMTRVLTGEALVGEHDRLQERINQVVDRIEASLRQCLKIAISQGAFPPDADVP
VRAALIVATVQGQWHRYAKSGFRKLPSENADAQLRVLLG