Protein Info for RR42_RS00215 in Cupriavidus basilensis FW507-4G11

Annotation: branched-chain amino acid ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 PF01425: Amidase" amino acids 26 to 418 (393 residues), 275.9 bits, see alignment E=3.7e-86

Best Hits

KEGG orthology group: K01426, amidase [EC: 3.5.1.4] (inferred from 68% identity to har:HEAR3253)

Predicted SEED Role

"putative amidase"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.4

Use Curated BLAST to search for 3.5.1.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YAB8 at UniProt or InterPro

Protein Sequence (429 amino acids)

>RR42_RS00215 branched-chain amino acid ABC transporter ATP-binding protein (Cupriavidus basilensis FW507-4G11)
MNDFLALPARELAARMARRELSVQALVRAYIARIDAAEAGILAWQHFDGAQALQQARQLD
AGPALGALHGLPIGVKDLMDTADMPTTYGSPIYAGHRPVMDAACVAMARAAGAVVMGKTV
TTEFATFQPGPTRNPRAPADAPRTPGGSSSGSAAAVAAGMVPIAFGTQTAGSIIRPAAYC
GVVGYKPTFGTLPSAGIKSLSPSLDTVGVLARCVDDAAFFIGAMARLPLTPPQAGQATRL
RVGICRTPHWERAGDDSRRALDTAARWLEGRGAVLSDLILPAQFDELTQAQIDIMAYEAA
AAFAPEMRARPDGFSSGFAALLAAGRGIDGSRFFAAQALAGSARRAFGQMFDSVDIVLAP
SAPGEAPAGLGATGDPMFNRMWTLLGNPCVHVPTSTGAHGMPVGVTLIGPCRGDARVLAA
AQALERCVA