Protein Info for RALBFv3_RS21105 in Ralstonia solanacearum IBSBF1503
Annotation: CusA/CzcA family heavy metal efflux RND transporter
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (1052 amino acids)
>RALBFv3_RS21105 CusA/CzcA family heavy metal efflux RND transporter (Ralstonia solanacearum IBSBF1503) MIDALVRGALKQRLVVAVVAAVLLFFGVDAARKLSLDAFPDVTNVQVQIATEAPGRSPEE VERFVTVPVEMAMTGLPALTEMRSLNKPGLSLITLVFTDETDVYFARQLVMERIMEVQSR MPVGVTPVLGPVSTGLGEVYQYTLDRPDDGSKELSVEELTRRRIAQDWVVRPLLRSIPGV AEINSQGGYEKQYQVLVNPERLRHHNVTVQQVFEALAANNANSGGGVLPHFAEQYLIRGV GLVRDINDIGAIVLKEVGGTPLTVRDVAEVKIGTAVRAGAVVKNGVTESVGGVVMMMRGG NAKEVVARIQERVKAVNDNGMLPDGLKIVPYYERSELVDSALNTVIKVLLEGVVLVVLVL LLFLGDIRSSLIVVGTLVLTPLLTFMAMNRLGISANLMSLGGLAIAIGLMVDGSVVVVEN AFAHLAKPRDPNESRVRIILHAVTEVATPVIFGVGIIILVFLPLMTLQGMEGKMFAPLAF TIAIALFISLVLSLTLTPVLSSYLLKPKASKHAGGDHGDHGHDAHAQHDEHDTWLIRKLK KPYLRLLELSLNNGRKTVVVAVAVFFATGALMPFLGTAFIPEMKEGSIVPGINRAPNISL EESIRMEMEAMRLVMQVPGVRSAVSGVGRGESPADPQGQNESTPIVSLKPRDQWPKGWTQ DDIAEGMRRALQALPGVQIVMAQPISDRVDEMVTGVRSDVAIKVFGDDLAVLREKAEAIA RVAQGIQGAQDMRVERITGQQYLQIAIDRQAIARHGLNASDVHNVIETAIGGKEATEVFE GERRFGAVVRLPEAYRGSVEAIRNLIVAAPNGAQVPLESIARIDVTDGPAQISRELGKRR VVVGVNVRDRDLGGFVAELQAAVAQKVKLPEGYYLEWGGQFQNMERAMGHLKVIVPITVA AIFFLLFLLFNSVRYATLIILVLPFASVGGIIGLFVTGEYLSVPASVGFVALWGIAVLNG VVLVSTIRNLREQGMSIDESVRLGARLRFRPVMMTATVAMLGLIPFLFATGPGAEVQRPL AIVVIGGLLTCTLLTLVMLPTLYKWFDEEARS