Protein Info for RALBFv3_RS00485 in Ralstonia solanacearum IBSBF1503

Annotation: SPFH/Band 7/PHB domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF01145: Band_7" amino acids 24 to 195 (172 residues), 119.6 bits, see alignment E=1.6e-38 PF16200: Band_7_C" amino acids 244 to 304 (61 residues), 89.8 bits, see alignment E=9e-30

Best Hits

Swiss-Prot: 46% identical to YH77_SCHPO: Uncharacterized protein C16G5.07c (SPBC16G5.07c) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: None (inferred from 99% identity to rso:RSc1423)

Predicted SEED Role

"Putative stomatin/prohibitin-family membrane protease subunit YbbK" in subsystem YbbK

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (308 amino acids)

>RALBFv3_RS00485 SPFH/Band 7/PHB domain protein (Ralstonia solanacearum IBSBF1503)
MFELGTLALIVLFAAIVLIAQSIKIVPQQHAWILERLGKYHATLSPGLNIVLPFVDRVAY
KHVLKEIPLDVPSQICITKDNTQLQVDGILYFQVTDPMRASYGSSNFVIAITQLAQTTLR
SVVGKLELDKTFEEREFINHSVVNALDEAASNWGVKVLRYEIKDLTPPKEILHAMQAQIT
AEREKRALIAASEGKRQEQINLASGAREAAIQKSEGEKQAAINRAQGEAAAIVAVAEANA
QAIQKVGHAIRTEGGIDAVNLKVAEEYVAAFGNLAKQGNTLIVPGNLGDLSTMIASALQI
VKQQRPTA