Protein Info for Psyr_4769 in Pseudomonas syringae pv. syringae B728a

Annotation: Major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 transmembrane" amino acids 17 to 38 (22 residues), see Phobius details amino acids 55 to 75 (21 residues), see Phobius details amino acids 83 to 102 (20 residues), see Phobius details amino acids 108 to 129 (22 residues), see Phobius details amino acids 141 to 162 (22 residues), see Phobius details amino acids 169 to 188 (20 residues), see Phobius details amino acids 203 to 223 (21 residues), see Phobius details amino acids 231 to 250 (20 residues), see Phobius details amino acids 270 to 295 (26 residues), see Phobius details amino acids 306 to 327 (22 residues), see Phobius details amino acids 335 to 354 (20 residues), see Phobius details amino acids 360 to 380 (21 residues), see Phobius details amino acids 400 to 422 (23 residues), see Phobius details amino acids 438 to 460 (23 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 20 to 419 (400 residues), 230.5 bits, see alignment E=1.8e-72 PF07690: MFS_1" amino acids 21 to 412 (392 residues), 148.2 bits, see alignment E=1.5e-47

Best Hits

Swiss-Prot: 46% identical to MDTD_YERE8: Putative multidrug resistance protein MdtD (mdtD) from Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_4769)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZM26 at UniProt or InterPro

Protein Sequence (470 amino acids)

>Psyr_4769 Major facilitator superfamily (Pseudomonas syringae pv. syringae B728a)
MQNSAAPIMDEKTLRWMPWVIAIAFFMQSLDGTILNTALPSMARSLAEDPLRMQSVVIAY
MLTIALLIPASGWIADRFGIKRIFFSAILLFSFGSLLCALSWSLNVLVAARVIQGLGGAL
MLPIGRLIVLRAYPRSELVRIMGFITVPGLLGPLLGPTLGGWMVEYLSWHWIFLINIPVG
ILGCYAVKHFIPDLPGGGRTRFDGVGFILFGAAMILITIALEGLGELHLPHMRVVLLLFA
GMGCLAAYWLRAGHIESPLFAPSLFRTRTFAVGIMGNLFARLGSGALPFLVPLLLQVALG
YSPSQAGMSMLPLAAAGMFAKTVARWLIERLGYRVILTGNTLLLGILLASLALVDVQTPY
WVLLVHLGLLGAVNSLQFTAMNTVTLIDLDDASAASGNSLLSVVAQLSLSLGVASAAALL
GGFSEEVATGEVSSMLGAFQMTFLSVGVLAMFAAGIFLQLPAKEPRMAKA