Protein Info for Psyr_4295 in Pseudomonas syringae pv. syringae B728a

Annotation: Histone deacetylase superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 PF00850: Hist_deacetyl" amino acids 19 to 286 (268 residues), 187.6 bits, see alignment E=1.8e-59

Best Hits

Swiss-Prot: 49% identical to Y1628_SYNP2: Uncharacterized protein SYNPCC7002_A1628 (SYNPCC7002_A1628) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6)

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_4295)

Predicted SEED Role

"Deacetylases, including yeast histone deacetylase and acetoin utilization protein" in subsystem Hydantoin metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZNE7 at UniProt or InterPro

Protein Sequence (305 amino acids)

>Psyr_4295 Histone deacetylase superfamily (Pseudomonas syringae pv. syringae B728a)
MSLPLIYHEDYSPDFPADHRFPMDKFRLLRDYLIDSGLTSDVQLMRPELCPADILALAHD
PSYISRYLSGDLSREDQRRLGLPWSEALARRTIRAVGGSLLTAEQALKHGLACHLAGGTH
HAHYDYPAGFCIFNDLAVISQYLLQSGRVDKVLIFDCDVHQGDGTARILADTEDAITVSL
HCEKNFPARKAQSDWDIPLPMGMGDADYLNVVDDLLNYLLPLYKPDLVLYDAGVDVHKDD
ALGYLQLTDQGLANRDEAVLRHCLSRDIPVMGVIGGGYSKDRLALARRHGILHHSAQRVW
NDMGL