Protein Info for Psyr_4004 in Pseudomonas syringae pv. syringae B728a

Annotation: Drug resistance transporter EmrB/QacA subfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 498 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 49 to 67 (19 residues), see Phobius details amino acids 79 to 98 (20 residues), see Phobius details amino acids 105 to 128 (24 residues), see Phobius details amino acids 139 to 159 (21 residues), see Phobius details amino acids 165 to 187 (23 residues), see Phobius details amino acids 199 to 218 (20 residues), see Phobius details amino acids 230 to 249 (20 residues), see Phobius details amino acids 269 to 291 (23 residues), see Phobius details amino acids 304 to 323 (20 residues), see Phobius details amino acids 335 to 352 (18 residues), see Phobius details amino acids 358 to 381 (24 residues), see Phobius details amino acids 401 to 422 (22 residues), see Phobius details amino acids 471 to 491 (21 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 14 to 419 (406 residues), 245.4 bits, see alignment E=5.7e-77 PF07690: MFS_1" amino acids 18 to 410 (393 residues), 193.9 bits, see alignment E=7.7e-61 PF06609: TRI12" amino acids 31 to 290 (260 residues), 39.2 bits, see alignment E=6.7e-14 PF00083: Sugar_tr" amino acids 48 to 182 (135 residues), 57.5 bits, see alignment E=2.4e-19 PF12832: MFS_1_like" amino acids 68 to 170 (103 residues), 27.9 bits, see alignment E=2.6e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_4004)

Predicted SEED Role

"drug resistance transporter, EmrB/QacA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZP88 at UniProt or InterPro

Protein Sequence (498 amino acids)

>Psyr_4004 Drug resistance transporter EmrB/QacA subfamily (Pseudomonas syringae pv. syringae B728a)
MTSLNQTPPAIRSILFALMMAVLLSALDQTIVAVSMPAISAQFRDIDLLAWVISAYMVSL
TVAVPIYGKLGDLYGRRKLMLFGLGIFTLASLFCGLAQSMEQLVLARVLQGIGAGGMVSV
SQAIIADIVPPRERGRYQGYFSSMYAVASVAGPVLGGLMTEYLSWRWVFLINLPLGAAAL
IVAYRTLVGLPVPQRKPIIDYLGTVLMIIGLTALLLGITEIGQGHGLGDAEVQLLLGTAL
LTLAIFVWYERRTAEPLLPMHLFTNKSAVLCWCTVFFTSFQAISLIVLMPLRYQTVTGGG
ADSAALHLLPLAIGMPMGAYFAGRRTAHTGRYKPLILTGALLMPVAILGMAFTPPQSLIV
MSLFMVLTGVATGMQFPTSLVGTQNSVQPRDMGVATSTTNLFRSLGGAVGVALMSALLLA
MLQHTGVGQLGAGALGSEGSSGNVLLDSLNAATGPALETLRTELAVTFRNLLITSAAISL
LGLAAAAVMPNTLLRGRD