Protein Info for Psyr_3778 in Pseudomonas syringae pv. syringae B728a

Annotation: Substrate-binding region of ABC-type glycine betaine transport system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF04069: OpuAC" amino acids 29 to 316 (288 residues), 211 bits, see alignment E=1.2e-66

Best Hits

KEGG orthology group: K02002, glycine betaine/proline transport system substrate-binding protein (inferred from 100% identity to psb:Psyr_3778)

Predicted SEED Role

"Histidine transporter, periplasmic histidine-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZPW3 at UniProt or InterPro

Protein Sequence (337 amino acids)

>Psyr_3778 Substrate-binding region of ABC-type glycine betaine transport system (Pseudomonas syringae pv. syringae B728a)
MKSITRLLGCSLLALGLLGQTATAAEKAKPIQFGALTWESGSLITEVLRTIVEKGYGYPT
DTLPGSTVSLETALAKNDIQVIAEEWTGRSPVWVKAEEEGKVLGLGNIVKGATEGWWVPE
YVIKGDAAKGIKPLAPDLKSVADLARYKDVFKDPESPDKGRFLNSPSGWTSEIVNTQKLK
AYGLADSFVNFRTGSGAALDAEVASAIRRGKPVLFYYWSPTPLLGKYKLIKLDEPAFDAE
AWKTLTDASNPNPRGTSSLAATLSIGVSAEFSKQYPELVSVFKGVDFPIDLLNKTLGEMS
DKHEDAKVVAARFLKQHPEVWKAWLPADVATRVSGSL