Protein Info for Psyr_3085 in Pseudomonas syringae pv. syringae B728a

Annotation: ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 94 to 115 (22 residues), see Phobius details PF00672: HAMP" amino acids 114 to 166 (53 residues), 34.6 bits, see alignment 3e-12 PF00512: HisKA" amino acids 175 to 232 (58 residues), 38.4 bits, see alignment E=1.6e-13 PF02518: HATPase_c" amino acids 282 to 390 (109 residues), 86.8 bits, see alignment E=2.1e-28

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_3085)

Predicted SEED Role

"two-component system sensor protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZRV5 at UniProt or InterPro

Protein Sequence (391 amino acids)

>Psyr_3085 ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal (Pseudomonas syringae pv. syringae B728a)
MRHFFRHRQKPLWHWVGMRMSMLAVGAVIVIAFCMWLHVTVSDWLTLQAMPADVRMEFLR
LQAEPTLDMAKLRELFVEYYPIENLLPGIANKEWWVLAALVSIAIPIILFFGFLFSRPLS
SQFSSIARGARQVAQGDFKTRLPMSTNGPDELQALVSDFNTMTTQLGRYELEVSESSAMI
AHELRTPLNAAMGRIQGMIDEVFPRDLAQLEMVHRQLGQLNKLVSDLHLLSLASAGQLTL
DKTEFSLEKLVVERLGWFAAPLDEAGVVVTIDIPRKLTVNADRDRIGQVVNILVDNALRY
SAMGGELLIVGRASAGRMELSVLDRGPGFDSENLEQVFDRFWRAERSRARYSGGSGLGLS
IARAICLEHDGTIEVSNRPGGGSVIRLEIPG