Protein Info for Psyr_2198 in Pseudomonas syringae pv. syringae B728a

Annotation: Urease, beta subunit:Urease, gamma subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 231 PF00547: Urease_gamma" amino acids 1 to 99 (99 residues), 134.9 bits, see alignment E=1.1e-43 TIGR00193: urease, gamma subunit" amino acids 1 to 100 (100 residues), 131.8 bits, see alignment E=9.4e-43 TIGR00192: urease, beta subunit" amino acids 111 to 211 (101 residues), 132.3 bits, see alignment E=6.8e-43 PF00699: Urease_beta" amino acids 112 to 208 (97 residues), 137.4 bits, see alignment E=1.4e-44

Best Hits

Swiss-Prot: 100% identical to URE23_PSEU2: Urease subunit gamma/beta (ureAB) from Pseudomonas syringae pv. syringae (strain B728a)

KEGG orthology group: K14048, urease subunit gamma/beta [EC: 3.5.1.5] (inferred from 100% identity to psb:Psyr_2198)

MetaCyc: 50% identical to urease subunit alpha UreA (Helicobacter pylori 26695)

Predicted SEED Role

"Urease beta subunit (EC 3.5.1.5) / Urease gamma subunit (EC 3.5.1.5)" in subsystem Urea decomposition (EC 3.5.1.5)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.5

Use Curated BLAST to search for 3.5.1.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZUD1 at UniProt or InterPro

Protein Sequence (231 amino acids)

>Psyr_2198 Urease, beta subunit:Urease, gamma subunit (Pseudomonas syringae pv. syringae B728a)
MLLTPTELERLTLYTAAELSRKRRSKGLRLNFPEASALIADEILEGAREGRSVAELIGFG
STILNTDDVMPGVADLLPVLQVEGTFPDGTKLVTVHQPIRPGQLPLAVMPTPGEILAPDG
DIHLNGDRPTATLRAINTGDRPVQIGSHYHFFEVNKALDFPRERAFGMHLDIPAGTAVRF
EPGELREVQLVQFGGTGDIHGFSGLTNGNLHDPACKLAALERARAQFFKGA