Protein Info for Psyr_1981 in Pseudomonas syringae pv. syringae B728a

Annotation: PAS:GGDEF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 730 PF00989: PAS" amino acids 37 to 149 (113 residues), 24.4 bits, see alignment E=8.5e-09 amino acids 164 to 272 (109 residues), 24.6 bits, see alignment E=7.4e-09 PF08447: PAS_3" amino acids 59 to 145 (87 residues), 43.6 bits, see alignment E=1.1e-14 TIGR00229: PAS domain S-box protein" amino acids 159 to 282 (124 residues), 55.1 bits, see alignment E=8.3e-19 PF13188: PAS_8" amino acids 163 to 211 (49 residues), 21.6 bits, see alignment 5.7e-08 PF13426: PAS_9" amino acids 173 to 272 (100 residues), 32.4 bits, see alignment E=3.2e-11 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 283 to 451 (169 residues), 152 bits, see alignment E=1.2e-48 PF00990: GGDEF" amino acids 287 to 448 (162 residues), 162 bits, see alignment E=3.7e-51 PF00563: EAL" amino acids 469 to 707 (239 residues), 240 bits, see alignment E=8.4e-75

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_1981)

Predicted SEED Role

"Sensory box protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZUZ8 at UniProt or InterPro

Protein Sequence (730 amino acids)

>Psyr_1981 PAS:GGDEF (Pseudomonas syringae pv. syringae B728a)
MPNPPDNAAPKTTVQTASARLSLKDAERALQETRDRLELALDLAQMGTWDLDIVRNRLQA
SARAALLHGMPARTFDESGGQFFGSLPAEERRRMRAIYAAALETGQDCLQVTYRFQLKNG
TSRLLEGRARIYRDEQGQPVRLSGTLMDITQQCAQVALEASEEKFAKAFHSSPDSITITE
IDSGRYVEVNDGFSRLTGFSAHEVLGRTAHEVGIWTDTLQREHMLEELRQKGRVHHREMD
GRDKHGAPLVLDISVEFITLNNTACLLMNARDIGALKNAQAQIQHLAYHDPLTGLPNRAL
LLDRLSQQVSLLQHQNLRGALLFLDLDHFKHINDSLGHPVGDSVLSIIAARLEASVRQED
TVARLGGDEFVVLICGLEGSQDEVTRQVRELADNLRNLLAEPMFLDGHRLQVTPSIGVVL
IPDDGLTPADLLKRADIALYRAKDCGRNASQFFHVSMQQAVSQRLRLENDLRLALTRNEF
HLHFQAQVDCRNEYITGAEALLRWQHPEYGLLAPDQFVQILEESGMILEVGSHILNEACK
TGGLLLRQGLIPENRFLMGVNISPRQFLQHDFIERVERSLTLHQLPASMLKLEITEGIVI
QNLDDTILKMLSLKALGVSFAMDDFGTGYSSLTYLKRLPVDTLKIDQSFVQDATNDPNDA
EIIRAIVAMAQSLNLNVIAEGVETSEQLAFLEKVGCYTYQGYLFSEPLPGPQFESLLELK
RPAQQPAHQD