Protein Info for Psyr_1776 in Pseudomonas syringae pv. syringae B728a

Annotation: Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 543 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 29 to 30 (2 residues), see Phobius details amino acids 190 to 211 (22 residues), see Phobius details PF08269: dCache_2" amino acids 35 to 189 (155 residues), 128.2 bits, see alignment E=9.5e-41 PF17200: sCache_2" amino acids 40 to 190 (151 residues), 132.6 bits, see alignment E=3.1e-42 PF17201: Cache_3-Cache_2" amino acids 68 to 186 (119 residues), 43.3 bits, see alignment E=7.7e-15 PF00672: HAMP" amino acids 210 to 262 (53 residues), 48.8 bits, see alignment 1.8e-16 PF00015: MCPsignal" amino acids 329 to 509 (181 residues), 145.3 bits, see alignment E=4.4e-46

Best Hits

Swiss-Prot: 68% identical to MCPP_PSEPK: Methyl-accepting chemotaxis protein McpP (mcpP) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to psb:Psyr_1776)

Predicted SEED Role

"Methyl-accepting chemotaxis protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZVJ8 at UniProt or InterPro

Protein Sequence (543 amino acids)

>Psyr_1776 Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer (Pseudomonas syringae pv. syringae B728a)
MSMRSLSISRRLWLILVVSVLMLFVLSATLLRQLHNDLYQAKAEKTMHVVQTASGILSFY
QGLEAAGGMTREAAQQQALKEIKSLRYSQSDYFWINDLRPVMIMHPTNAKLEGQDLSTIK
DPDGFAVFNEMVTLVKAQGAGMVNYRWPKPGASEPVKKTSYVQLFQPWGWILGSGVYVDD
VAAEFKTQLWNAGMFIAGIVLIMVLLLVTIVRSIVRPLRAAVGAMASIASGESDLTRTLE
THGNDEITELGTHFNAFVAKLRNVVGQLQHSAVALGQASTDLGSDAEQAQSRSEQQSQQM
DLVATAVNEVTYGVQDVAKNAEHAASEMRDAESQAQQGQINIDNSLRQIEHLSSTIGQAV
QVMQSLASESTQIGSVLEVISSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRLLAQ
RTQKSTAEIQSMIERLQKHSDAAVKVIGDSSRSSQLTIEQANQAGQSLTSISQALRNLNS
LNASIASATLQQTHVVDDINQNVTQAAQLSQSTALAAEQSTSASLHLRGLSEELNTLLKQ
FRV