Protein Info for Psyr_1751 in Pseudomonas syringae pv. syringae B728a

Annotation: PpiC-type peptidyl-prolyl cis-trans isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 627 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details PF13624: SurA_N_3" amino acids 1 to 167 (167 residues), 147.5 bits, see alignment E=7.8e-47 PF13623: SurA_N_2" amino acids 2 to 144 (143 residues), 121 bits, see alignment E=9.3e-39 PF13145: Rotamase_2" amino acids 249 to 376 (128 residues), 57.5 bits, see alignment E=6.4e-19 PF13616: Rotamase_3" amino acids 265 to 364 (100 residues), 92.6 bits, see alignment E=6.1e-30 PF00639: Rotamase" amino acids 273 to 363 (91 residues), 98.8 bits, see alignment E=7.3e-32

Best Hits

KEGG orthology group: K03770, peptidyl-prolyl cis-trans isomerase D [EC: 5.2.1.8] (inferred from 100% identity to psb:Psyr_1751)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZVM3 at UniProt or InterPro

Protein Sequence (627 amino acids)

>Psyr_1751 PpiC-type peptidyl-prolyl cis-trans isomerase (Pseudomonas syringae pv. syringae B728a)
MLQNIRDNSQGWIAKTIIGLIIALMAFTGIEAMFTATSNKQNAAEVNGEDISQNELSQAV
DMQRRQLAQQLSQQLGKDFDPAMLDEKLLRESALKGLIDRKLLLQGAADARFSFSDAALD
QQLLQTPEFQVDGKFNADRFDQVIRQLGYSRLQFRQMLGQEMLIGQVRAGVAGSAFVTDA
QVEAFARLEKQTRDFASLTLPADTSAVKVTDDEVKAHYDEHAKEFMSPEQVVLDYIELKK
SSFFDKVQVKDEDLQAAYQKEIANLSEQRRAAHILIEVNDKLNDEQAKAKIEEIQQRLAK
GEDFAALAKEYSQDPGSSNKGGDLGYAGKGVYDPAFEEALYALNKDQVSQPVRTDFGWHL
IKLLGVEAPSVPSFASLKGKLTNDLKSQLVEQKFVEVTKQLEDSAFESSDLSQPAQDLGL
KVQTTAPFGREGGEGLTANRAVIQAAFSPEVLEEGANSNTLELDPETVVVVRSKEHLQPQ
QLPLESVASSIRAQLVKEHASAAAKAKGEALLAGLRDGKIPLAAKQEGRDWKVMEAVTRS
QEGVDPQVLQTLFRMPKPTGKDKPEFASITASDGSFVIVRLNGVNQAAAPTDAEKAQYRR
FLSSREGQQDFAAYRAQLESKAKIEKF