Protein Info for Psyr_1681 in Pseudomonas syringae pv. syringae B728a

Annotation: Major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 transmembrane" amino acids 21 to 46 (26 residues), see Phobius details amino acids 57 to 79 (23 residues), see Phobius details amino acids 91 to 126 (36 residues), see Phobius details amino acids 153 to 174 (22 residues), see Phobius details amino acids 180 to 200 (21 residues), see Phobius details amino acids 225 to 251 (27 residues), see Phobius details amino acids 265 to 283 (19 residues), see Phobius details amino acids 293 to 312 (20 residues), see Phobius details amino acids 318 to 339 (22 residues), see Phobius details amino acids 350 to 372 (23 residues), see Phobius details amino acids 378 to 398 (21 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 266 (237 residues), 85.9 bits, see alignment E=1.4e-28 amino acids 232 to 401 (170 residues), 51.4 bits, see alignment E=4e-18

Best Hits

Swiss-Prot: 59% identical to FSR_ECOLI: Fosmidomycin resistance protein (fsr) from Escherichia coli (strain K12)

KEGG orthology group: K08223, MFS transporter, FSR family, fosmidomycin resistance protein (inferred from 100% identity to psb:Psyr_1681)

MetaCyc: 59% identical to fosmidomycin efflux pump (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-41

Predicted SEED Role

"fosmidomycin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZVU3 at UniProt or InterPro

Protein Sequence (402 amino acids)

>Psyr_1681 Major facilitator superfamily (Pseudomonas syringae pv. syringae B728a)
MATSAPPATAKASTTPQASPLVMRIIGAVALAHLVNDLIQAILPSIYPMLKASYDLSFTQ
IGLITLTFQITASLLQPWVGYYTDRHPNPLVLPVGSICTLIGIVMMSMVGSFPLILLAAA
LIGIGSSTFHPEASRIARLASGGRYGLAQSTFQVGGNTGTAFGPLLAAAIIIPFGQGNVA
WIGLFALFSLGLLYAISRWYRTHLNLFKLKAGQAATHGLSRKRVIASLAVLAFLVFSKFF
YMTSLTSYFTFYLIEKFGLSVASSQLHLFLFLGAVAAGTFFGGPIGDRIGRKAVIWFSIL
GAAPFTLALPYADLFWTSVLSVIIGFVLASAFSAIVVYAQELVPGNVGMIAGLFFGLMFG
FGGIGAALLGYLADSHGILFVYTLCSYLPLLGILAILLPRTK