Protein Info for Pf6N2E2_6008 in Pseudomonas fluorescens FW300-N2E2

Annotation: Permease of the drug/metabolite transporter (DMT) superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 37 to 54 (18 residues), see Phobius details amino acids 66 to 84 (19 residues), see Phobius details amino acids 90 to 114 (25 residues), see Phobius details amino acids 121 to 139 (19 residues), see Phobius details amino acids 150 to 168 (19 residues), see Phobius details amino acids 186 to 204 (19 residues), see Phobius details amino acids 206 to 208 (3 residues), see Phobius details amino acids 214 to 233 (20 residues), see Phobius details amino acids 240 to 259 (20 residues), see Phobius details amino acids 269 to 287 (19 residues), see Phobius details PF00892: EamA" amino acids 27 to 138 (112 residues), 47.1 bits, see alignment E=1.5e-16 amino acids 149 to 285 (137 residues), 32.2 bits, see alignment E=6e-12

Best Hits

KEGG orthology group: None (inferred from 94% identity to pfl:PFL_4987)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161H9R7 at UniProt or InterPro

Protein Sequence (301 amino acids)

>Pf6N2E2_6008 Permease of the drug/metabolite transporter (DMT) superfamily (Pseudomonas fluorescens FW300-N2E2)
MSTNNNRAIIELTIGGLMLSLSALAVAFAHIGAGGAGFYRMLFASILFFLLLKVRKTPVL
LKSAKAQVYTALAGVFLAIDLVLWHQSIYIVGPGIGSILTNCQVFFMTLLGLYLLKEKPS
IYFLVSITLAFVGLYLLLLPEMTSAVGIKGVVYGVLSGLAYAICVYFLKVNTQLPDGGGD
KIAQMLNLSLWAALVLLTYALATGESLAIVDGQTLLMLIIYGVLVQFVGWLLVNRSIGAI
SLGLAGLILLLEPVITYFIDVTFLGKASSTLQICGALLTIFAVYIGSIKPPEKVQPLPEA
T